Fig. 1Endoscopic features of the ascending (A) and transverse (B) colon. A colonoscopy reveals several depressed flat lesions and elevated polyps, which are measuring up to 4 mm in size with whitish exudates.
Fig. 2(A) There is an infiltration of many histiocytes with ample granular eosinophilic cytoplasm with some lymphocytes and plasma cells (ascending colon). (B) Round basophilic structures are identified, measuring approximately between 1 µm and 10 µm in size within histiocytes, so-called Michaelis-Gutmann bodies (transverse colon).
Fig. 3Michaelis-Gutmann bodies are positively stained on von Kossa stain. (A) Hematoxylin and eosin stain. (B) von Kossa stain.
Table 1.Clinical features of previously reported colonic malakoplakia in a kidney transplant patient
Reference |
Site of involvement |
Complaints |
Presentation |
Age (yr)/Sex |
Shah et al. [5] |
Cecum ascending and sigmoid colon |
Diarrhea |
3-4 mm polypoid nodule |
45/M |
Berney et al. [2] |
Cecum and rectum |
Acute intestinal perforation |
Mass forming |
52/M |
Yousif et al. [6] |
Rectum |
Painful defecation |
Mass and fistulous tract forming |
40/M |
Present case |
From cecum to descending colon |
No symptom |
3-4 mm multiple polypoid nodules and depressed lesions |
55/F |