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The Korean Journal of Cytopathology 1995;6(2): 209-214.
Cytologic Features of Papnicolaou Smears of Malignant Melanoma Arising in Vagina: A Cese Report.
Myung Suk Kang, Bohng Hee Kim, Jae Hoon Park, Youn Wha Kim, Yong Koo Park, Ju Hie Lee, Moon Ho Yang
Department of Pathology, College of Medicine, Kyung Hee University, Korea.
Primary malignant melanoma of vagina is a rare tumor which is easily misinterpretated in routine cytologic examination. We lately experienced a case of primary malignant melanoma of the vagina with direct cervical extension diagnosed by Pap smear. The cervicovaginal smear showed variable sized clusters of epithelial cells or singly scattered abnormal epithelial cells. Most of the tumor cells had round hyperchromatic nuclei with prominent nucleoli and brownish pigments in cytoplasm. The cytologic findings are compared with histologic features of resected specimen.
Key Words: Malignant melanoma; Vagina; Cervix; Cytology