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The Korean Journal of Pathology 1992;26(3): 270-276.
Eosinophilic Granuloma of the Lung.
Sang Ae Yoon, Won Bo Jo, Yang Seok Chae, Kap No Lee
Department of Pathology, Korea University Guro Hospital, Seoul, Korea.
Eosinophilic granuloma of the lung, first described by Farrinaci et al. in 1951, is rare. A 35-year-old male smoker presented with recurrent pneumothorax. Open thoracotomy with bleb resection and biopsy was performed. Microscopically there was histological changes consistent with typical eosinophilic granuloma and intertitial fibrosis. The Langerhans cells showed positive reaction for S-100 protein and typical Birbeck granules in their cytoplasm. A brief summary of histopathological aspect of this disease and a review of literature are presented.
Key Words: Eosinophilic Granuloma; Lung; Fibrosis; Birbeck granule