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The Korean Journal of Pathology 1992;26(3): 209-214.
Ovarian mature cystic teratoma with histologic features of chronic thyroiditis: Histologic analysis of 4 cases.
Doo Hyun Chung, Weon Seo Park, Soo Min Kang, Eun Sil Yu, Seong Hoe Park
1Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
2Gyeong Sang National University College of Medicine, Korea.
3Department of Pathology, University of Ulsan, Korea.
We have reviewed ovarian mature cystic teratomas with features of chronic thyroiditis that were diagnosed at the department of pathology, Seoul National University Hospital during 7 years, 1984-1991. Twenty three case(8%) containing thyroid tissue among 285 ovarian mature teratomas were available for histopathologic examination. Among these, 4 cases(1.4%) showed lymphocytic infiltration with lymphoid follicle formation. These four cases were examined according to the strict histologic criteria of autoimmune thyroiditis and reactive non-autoimmune thyroiditis for the purpose of differentiation of pathogenesis. Two cases were similar to autoimmune in nature and the other two cases simply seemed to reflect reactive features to adjacent stimulating elements. In conclusion, thyroid tissue present in ovarian cystic teratoma may have histologic features of chronic thyroiditis of either autoimmune or non-autoimmune origin.
Key Words: Mature teratoma; Ovary; Chronic thyroiditis