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The Korean Journal of Pathology 1991;25(6): 581-588.
Clear Cell Sarcoma of the Kidney: Report of two cases.
Woo Hee Jung, Jee Young Han, So Yeon Park, Jae Eok Kim
1Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
2Department of Surgery, Sowha Chidern's Hospital.
ABSTRACT
Clear cell sarcoma is a rare malignant rumor of the kidney which occurs in children and is differentiated from Wilms' tumor by its different clinicopathologic features and natural history. Previous studies indicate that this tumor may be of mesenchymal cell origin; however, this has not been proven conclusively. Further accumulation and study need to be conducted in order to clarify the histogenesis of this tumor. We report two cases of clear cell sarcoma of the kidney which occurred in a 2 and a half-year old and a 2-year old boy. This report places special emphasis on the clinicopathologic characteristics of these two cases including electron microscopic and immunohistochemical findings. Attempts were also made to differentiate the clinicopathologic aspects of clear cell sarcoma from Wilms' tumor and speculate on the histogenesis of this rumor.
Key Words: Clear cell sarcoma; Malignant kidney tumor; Wilms' tumor; Immunohistochemistry