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The Korean Journal of Pathology 1987;21(3): 207-213.
Multiple Proliferating Trichilemmal Tumors with Ordinary Trichilemmal Cysts: A case report.
In Sook Kim, Jin Hee Sohn, Hye Seon Ahn, Jung Il Suh, Hyo Sook Park, Soo Jo Kim, Sook Ja Sohn
1Department of Pathology, National Medical Center, Seoul, Korea.
2Department of Dermatology, National Medical Center, Seoul, Korea.
Proliferating trichilemmal tumor is one of rare benign tumors of the skin appendages, considering as hamartoma of the terminal hair follicle, isthmic segment of the outer root sheath. We report a case of numerous proliferating trichilemmal tumors admixed with ordinary trichilemmal cysts with femilial history in 64-year-old man. He has total 157 lesions, which are chiefly located in scalp (48), back (32), and also face, neck, trunk, extremities. Histologically, the tumor is composed of irregularly arranged and ansatomosed trabeculae, lobules, or sheets of proliferated trichilemmal squamous epithelium with peripheral palisading of the basaloid cells. Several layers of squamoid or ovoid cells have PAS-positive clear cytoplasm. And it also shows abrupt amorphous, trichilemmal keratinization. Some squamous eddies with mild cellular atypism are associated, but definite invasion or other evidence of the malignancy is not found. usual multiple trichilemmal cysts are admixed with tumor and occasionally exhibit connection between them.