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The Korean Journal of Pathology 1987;21(3): 199-206.
Carcinoma In Situ of the Urinary Bladder with Transitional Cell Carcinoma of Prostate: A Histopathologic Study and Mapping of the Urothelial Lesions.
Seung Pyo Hong, Sang Sook Lee, Chai Hong Chung
Department of Pathology, Keimyung University School of Medicine, Taegu, Korea.
A 63-year-old male patient with extensive carcinoma in situ of the urinary bladder was found to have unsuspected transitional cell carcinoma of the prostate. Mapping of the totally embedded radical cystectomy specimen demonstrated diffuse, multifocal, epithelial abnormalities, ranging from mucosal atypia to the nonpapillary carcinoma in situ with extension to the urethra, prostatic ducts and glands, seminal vesicles and ureter, probably reflecting individual urothelial susceptibility in reaction to carcinogenic stimulus. The importance of prostatic assessment in the evaluation of the patient with carcinoma in situ of the urinary bladder is emphasized.
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