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The Korean Journal of Cytopathology 2003;14(2): 66-70.
Cytologic Features of Signet Ring Cell Carcinoma of the Uterine Cervix: A Report of Two Cases.
Hyun Yee Cho, Seung Yeon Ha, Jaegul Chung, Young Ha Oh, Dong Hae Chung, Na Rae Kim, Jong Min Lee, Eui Don Lee
1Department of Pathology, Gachon Medical School Gil Medical Center, Incheon, Korea. hicho@ghil.com
2Department of Obstetrics and Gynecology, Gachon Medical School Gil Medical Center, Incheon, Korea.
ABSTRACT
Signet ring cell carcinoma is a rare type of mucinous adenocarcinoma of the uterine cervix. To the best of our knowledge, there is no report on cytologic findings of primary signet ring cell carcinoma of the uterine cervix in the literature. Recently, we experienced two cases of signet ring cell carcinoma of the uterine cervix. The finding of characteristic signet ring cells on cervicovaginal smear led to the diagnosis of signet ring cell carcinoma. However, primary signet ring cell carcinoma could not be cytologically distinguished from more common metastatic tumor. Therefore, diagnosis rests upon the recognition of signet ring cells and the absence of signet ring cell carcinoma elsewhere.
Key Words: Signet ring cell carcinoma; Cervix uteri; Cytology; Cervicovaginal smear