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JPTM > Volume 44(4); 2010 > Article
The Korean Journal of Pathology 2010;44(4): 420-425.
doi: https://doi.org/10.4132/KoreanJPathol.2010.44.4.420
Solitary Fibrous Tumor of the Kidney: A Report of Two Cases with Review of Literature.
Sun A Kim, Jung Eun Hwang, Jae Y Ro, Kyung Ja Cho, Cheryn Song, Mi Jung Kim
1Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. mjkim1103@amc.seoul.kr
2Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
ABSTRACT
Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm usually occurring in the pleura. Kidney is one of the rarest sites for SFT. We report here on two cases of renal SFT found in 30-year-old and 33-year-old men with review of the literatures. Both cases manifested as well-enhanced solid masses in kidney and radical nephrectomies were done. The tumors consisted of bland-looking spindle cells arranged in short, ill-defined fascicles and storiform pattern with characteristic hemangiopericytoma-like blood vessels. The tumor cells were strongly positive for CD34 and CD99, focally positive for bcl-2, and negative for cytokeratin and human melanoma black-45 on immunohistochemical stainings. Possibility of SFT should be considered in the differential diagnosis of a renal mass which consists of benign-looking spindle cells and hemangiopericytomatous blood vessels. Immunohistochemical staining for CD34 is essential to confirm the renal solitary fibrous tumor.
Key Words: Solitary fibrous tumor; Kidney; Immunohistochemistry