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The Korean Journal of Cytopathology 1999;10(2): 151-155.
Bronchial Brushing and Bronchial Washing Cytologic Features of Primary Malignant Fibrous Histiocytoma of the Lung: A Case Report .
Mi Ok Park, Wook Su Ahn
Departments of Pathology, School of Medicine, Catholic University of Taegu-Hyosung, Taegu, Korea. mopark@cuth.cataegu.ac.kr
A case of primary malignant fibrous histiocytoma(MFH) of the lung occurring in a 62-year-old man is presented. After preoperative bronchial brushing and washing cytologic diagnosis of poorly differentiated carcinoma, surgical resection and lymph nodes dissection were performed. Subsequent histologic examination revealed a primary MFH. The diagnosis was confirmed by electron microscopic and immunohistochemical examinations. The review of the bronchial brushing and washing cytologic features disclosed many bipolar and a few unipolar spindle tumor cells with a "comet" configuration, mainly single cells, but also forming loose clusters. The nuclei were elongated and hyperchromatic and contained one or more irregular nucleoli. Scattered bizarre, multinucleated tumor giant cells were also present.
Key Words: Lung; Malignant fibrous histiocytoma; Bronchial brushing; Bronchial washing; Cytology