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The Korean Journal of Pathology 2002;36(3): 195-198.
Pleomorphic Hyalinizing Angiectatic Tumor of Soft Parts: A Case Report.
Young Chae Chu, Sun Keun Choi, In Suh Park, Hye Seung Han, Jee Young Han, Joon Mee Kim
1Department of Anatomical, Inha University Hospital, Incheon, Korea. ycchu@inha.ac.kr
2Department of Pathology, Inha University Hospital, Incheon, Korea.
3Department of General Surgery, Inha University Hospital, Incheon, Korea.
ABSTRACT
A case of rare pleomorphic hyalinizing angiectatic tumor (PHAT) of soft parts is reported. A 35-year-old woman presented with a subcutaneous solid mass in the left inguinal area, which had been present for 3 months, was presented to us. The tumor was histologically characterized by sheets of mitotically inactive oval and pleomorphic cells, mono-and multinucleated giant cells, intranuclear cytoplasmic inclusions, and prominent clusters of thinwalled ectatic vessels with perivascular hyalinization. A focal hemangiopericytoma-like vascular pattern, pseudovascular spaces, stromal collagen with degenerative change and abundant mast cells were observed. The tumor cells were reactive for vimentin and CD34. This tumor shared several features with malignant fibrous histiocytoma, ancient schwannoma, giant cell angiofibroma, giant cell fibroblastoma and solitary fibrous tumor. The patient was well with no evidence of disease for 10 months.
Key Words: Soft Tissue Neoplasms; Antiqens, CD34