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The Korean Journal of Pathology 1999;33(6): 471-473.
Choroidal Metastasis of Adenocarcinoma of the Lung: A case report.
Seong Hwan Park, Ju Han Lee, Jeong Seok Moon, Jong Sang Choi
Department of Anatomic Pathology, Guro Hospital, College of Medicine, Korea University, Seoul 152-703, Korea.
ABSTRACT
Choroidal metastatic carcinoma is very rare. We recently experienced a case of lung adenocarcinoma which presented to the clinic with ocular symptoms. This 57-year-old Korean male patient visited the department of ophthalmology due to decreased visual acuity and pain of the left eye. On MRI scan, a nodule was attached to the retina of the left eyeball. On simple chest radiograph, a large amount of pleural effusion was noted in the left pleural cavity. Emergency enucleation of the left eyeball was done with an impression of malignant melanoma causing an intractable ocular pain. Grossly, the lesion in the eyeball was rising from the choroid. On histologic examination, tumor cells formed many irregular, small gland-like structures. The tumor cells showed alcian blue-positive mucin in the cytoplasm and glandular lumens and were positive for CEA. Chest CT scan was performed postoperatively and showed a huge mass in the left lower lobe and multiple nodular opacities in both lung fields. Bronchoscopic biopsy revealed moderately differentiated adenocarcinoma similar to that of the eyeball.
Key Words: Choroidal metastasis; Lung cancer; Adenocarcinoma