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The Korean Journal of Pathology 1998;32(9): 697-699.
Well-Differentiated Papillary Mesothelioma of the Peritoneum: A case report .
Yi Kyeong Chun, Yee Jeong Kim, Sung Ran Hong
Department of Pathology, Sungkyunkwan University, Samsung Cheil Hospital Seoul, Korea.
Well-differentiated papillary mesothelioma (WDPM) of the peritoneum is considered to be a distinct subtype of peritoneal mesothelioma and has mostly behaved in a benign fashion. We report a case of WDPM in a 48-year-old-woman. It was incidentally found during a hysterectomy for a uterine cervical carcinoma. Grossly, the tumor was composed of multiple peritoneal nodules, measuring up to 2 cm. Microscopically, the nodules showed well-developed papillae lined by a single layer of cuboidal mesothelial cells. Immunohistochemical staining revealed a positive reaction for cytokeratin and a negative reacion for carcinoembryonic antigen and Leu-M1. Ultrastructurally, the tumor cells showed numerous long, slender microvilli and desmosomes.
Key Words: Well differentiated papillary mesothelioma; Peritoneum; Mesothelioma