| Home | E-Submission | Sitemap | Contact Us |  
JPTM > Ahead-of Print

doi: https://doi.org/10.4132/jptm.2020.05.17    [Epub ahead of print]
Appendiceal actinomycosis mimicking appendiceal tumor, appendicitis or inflammatory bowel disease
You-Na Sung , Jihun Kim
Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Corresponding Author: Jihun Kim ,Tel: +82-2-3010-4556, Fax: +82-2-472-7898, Email: jihunkim@amc.seoul.kr
Received: March 31, 2020;  Revised: May 12, 2020  Accepted: May 17, 2020.  Published online: June 26, 2020.
ABSTRACT
Appendiceal actinomycosis is very rare and its diagnosis is often difficult even in surgically resected specimens. Here we report two cases of appendiceal actinomycosis confirmed by pathologic examination of surgically resected specimens. Characteristic histologic features included transmural chronic inflammation with Crohn-like lymphoid aggregates and polypoid mucosal protrusion into cecal lumen through fibrous expansion of the submucosa. Chronic active inflammation involved the mucosa of the appendix and cecum around the appendiceal orifice. Crohn’s disease with predominant cecal involvement and inflammatory pseudotumor were considered as differential diagnoses. Careful examination revealed a few actinomycotic colonies in the mucosa, confirming the diagnosis. A high index of suspicion with awareness of the characteristic histologic features might prompt careful inspection for the actinomycotic colonies, leading to the appropriate diagnosis of this rare disease.
Key Words: Appendix; Actinomycosis; Mycetoma; Pathology
TOOLS
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
CrossRef TDM  CrossRef TDM
  E-Mail
Share:      
METRICS
0
Crossref
0
Scopus
187
View
4
Download
Related article