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JPTM > Ahead-of Print

doi: https://doi.org/10.4132/jptm.2017.11.21    [Epub ahead of print]
Primary Cutaneous Mucinous Carcinoma with Extramammary Paget’s Disease: Eccrine or Apocrine?
Sun-Ju Oh, Young-Ok Kim
Department of Pathology, Kosin University Gospel Hospital, Busan, Korea
Corresponding Author: Sun-Ju Oh ,Tel: +82-51-990-6744, Fax: +82-51-990 3080, Email: 10highpowerfield@gmail.com
Received: October 26, 2017;  Revised: November 17, 2017  Accepted: November 21, 2017.  Published online: January 25, 2018.
Primary cutaneous mucinous carcinoma (PCMC) is an uncommon tumor of the sweat gland origin. The occurrence of PCMC is mostly in middle-aged and older patients, with a slight male predominance. Most cases of PCMC arise on the head, with a preference for eyelids. The histogenesis of PCMC, whether eccrine or apocrine, remains controversial. We report a rare case of PCMC with secondary extramammary Paget’s disease in the groin of a 75-year-old man, which favored an apocrine origin. Furthermore, based on a review of the literature, we provide several histologic clues that can be used to differentiate PCMC from metastatic mucinous carcinoma.
Key Words: Cutaneous mucinous carcinoma; Skin adnexal tumor; Apocrine carcinoma; Paget’s disease, extramammary