1 [15] |
Age: 51 yr |
Size: 4 cm |
Unknown |
Unknown |
- |
Gyn hx: unknown |
Location: lateral wall of the uterine body |
Clinical sign: unknown |
Micro: |
Glands with no epithelial cell atypia |
Sarcomatous component with cell pleomorphism and a high mitotic count |
Accompanied by adenomyosis |
Tumor marker: unknown |
|
2 [13] |
Age: 20 yr |
Size: unknown |
Hysterectomy |
Two years after surgery, no evidence of recurrent disease |
Stromal overgrowth |
Gyn hx: null |
Location: right anterolateral portion |
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Clinical sign: a longstanding history of menorrhagia and vaginal bleeding |
Micro: |
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Florid adenomyosis with extensive myometrial invasion, expansile growth within the myometrium, and intravascular invasion in the myometrium |
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Tumor marker: β-hCG 50–80 mIU/mL |
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3 [2] |
Age: 46 yr |
Size: unknown |
Myomectomy |
Unknown |
- |
Gyn hx: para 1 |
Location: subserosal mass arising from the posterior surface of the uterus |
Additional TAH, BSO, and bilateral pelvic lymphadenectomy |
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Clinical sign: vaginal bleeding |
Micro: |
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Adenomyoma with focal predominant endometrial stroma and periglandular cuffs |
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Endometrial stromal cells in the periglandular cuffs showing mild and focal moderate cytological atypia with sparse mitotic figures, including an occasional atypical form |
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Tumor marker: unknown |
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4 [5] |
Age: 38 yr |
Size: 1.5 cm |
Exploratory laparotomy, TAH, LSO, and omentectomy |
Disease-free 30 mo after treatment |
Heterologous element (rhabdomyosarcoma) |
Gyn hx: gravida 1, para 0 |
Location: right cornual area |
Adjuvant cisplatin, ifosfamide, and mesna |
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Clinical sign: chronic pelvic pain and dysmenorrhea |
Micro: |
5,500 cGy to the abdominal wall |
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Irregular glands with benign epithelium surrounded by a hypercellular spindle cell stroma showing rare mitoses, mild nuclear hyperchromasia, and pleomorphism |
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Tumor marker |
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CEA and AFP: normal |
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CA125: 45 U/mL |
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5 [10] |
Age: 52 yr |
Size: uncheckable (no distinct mass formation) |
Radical hysterectomy with BSO and lymph node dissection and debulking of the pelvic mass |
Unknown |
Extrauterine pelvic mass (19 cm in diameter) diagnosed as adenosarcoma with rhabdomyosarcomatous differentiation and stromal overgrowth |
Gyn hx: gravida 3, para 3 |
Location: uterine fundus |
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Peri-menopausal |
Micro: |
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Diffuse adenomyosis with focal stromal expansion, consisting of a hypercellular proliferation of moderately atypical spindle cells with mitotic activity around benign endometrial glands and infiltrating the anterior myometrium |
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Clinical sign: none |
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Tumor marker |
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CA125: 258 U/mL |
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6 [14] |
Age: 53 yr |
Size: unknown |
Unknown |
Unknown |
Developed breast carcinoma and received adjuvant chemotherapy including tamoxifen |
Gyn hx: unknown |
Location: unknown |
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Clinical sign: unknown |
Micro: |
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Uterine adenosarcoma following an adenomyoma |
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Tumor marker: unknown |
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7 |
7 Age: 40 yr |
Size: 7.5 cm |
Laparoscopically assisted TVH |
No evidence of recurrence to date |
This case |
Gyn hx: gravida 2, para 2 |
Location: uterine fundus |
Additional BSO |
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Clinical sign: sudden-onset suprapubic pain and initial low back pain |
Micro: |
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Dilated glandular elements and abundant, hypercellular stromal elements |
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Expansile growth within the myometrium with extensive myometrial invasion and focal infiltration with expansile margin into the subserosa |
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Focal involvement of adenomyosis |
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Tumor marker |
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CA125: 5,000 U/mL |
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CA19-9: 39 U/mL |
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β-hCG, AFP: normal |
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