Pathology Unit, Neuropathology Service, Mexico General Hospital, Mexico City, Mexico
© 2015 The Korean Society of Pathologists/The Korean Society for Cytopathology
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Conflicts of Interest
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Case No. | Reference | Age/Sex | Location | Grade according to the described features of the glial component | Outcome (follow-up) |
---|---|---|---|---|---|
1 | Friede (1978) [1] | 3.9 yr/F | Lower medulla oblongata | Dedifferentiation of the glial component | Died (3 mo) |
2 | Snipes et al. (1991) [8] | 2 mo/F | Right thalamus and floor of the fourth ventricle | Anaplastic astrocytoma, WHO grade III (mitoses up to 5 per 10-HPF) | Died (16 mo) |
3 | Vazquez et al. (1991) [5] | 11 mo/F | Right temporal lobe | Anaplastic astrocytoma, WHO grade III (pleomorphism and numerous MFs) | Alive (2 yr) |
4 | Schober et al. (1992) [9] | 18 yr/M | Right frontal lobe | Anaplastic astrocytoma, WHO grade III (foci of pleomorphism, sparse and abnormal MFs) | Alive (7 days) |
5 | Cerda-Nicolas and Kepes (1993) [10] | 4 yr/F | Fourth ventricle, extending to the prepontine cistern and left temporal lobe | Anaplastic astrocytoma, WHO grade III | No data |
6 | Cerda-Nicolas and Kepes (1993) [10] | 9 yr/F | Left parietal lobe | Anaplastic astrocytoma, WHO grade III (pleomorphism and ocassional MFs) | Alive (5.5 mo) |
7 | Caldemeyer et al. (1995) [11] | 8 yr/M | Right temporal lobe | Anaplastic astrocytoma, WHO grade III (numerous MFs) | No data |
8 | Sharma et al. (1998) [4] | 54 yr/F | Right parietal lobe | Anaplastic astrocytoma, WHO grade III (pleomorphism, MFs and 10.5% of PI) | Died (6 mo) |
9 | Kim et al. (2003) [12] | 25 yr/M | Left parietal lobe | Anaplastic astrocytoma, WHO grade III (up to 35.8% of PI) | Alive (2 mo) |
10 | Gargano et al. (2014) [2] | 10.7 yr/F | Left fronto-parietal lobe | Anaplastic astrocytoma, WHO grade III (mild to moderate pleomorphism with up to 10% of PI) | Alive (2 yr) |
Subtotal (10 cases) | Mortality rate (cases with available data) (5/8) = 62.5% | ||||
11 | Bastos Leite et al. (2002) [13] | 47 yr/F | Left parietal lobe | Glioblastoma, WHO grade IV (nuclear atypia, endothelial proliferation, necrosis and mitoses) | Died (1 yr) |
12 | Present case | 50 yr/F | Left parieto-temporal lobe | Glioblastoma, WHO grade IV (microvascular proliferation, palisading necrosis and up to 50% of PI) | Died (1 mo) |
Subtotal (2 cases) | Mortality rate (2/2) = 100.0% | ||||
Total (12 cases) | Overall mortality rate (cases with available data) (7/10) = 70.0% |