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The Korean Journal of Pathology 1980;14(3): 33-36.
악성신경초종 2예
Malignant Schwannoma -A report of 2 cases-
During the past 3 years, the authors experienced 2 cases of malignant schwannoma. The first case was a 27 years old male who had clinical manifestations of von Recklinghausen's disease. A well circumscribed, ovoid tumor mass was located at extrapleural space at the level of 4th rib, measuring 9×7×7cm. Microscopically, the tumor consists of uniform, elongated, spindle cells and small number of bizzare, plump cells with frequent mitoses, and was in direct continuity with a neurofibroma. The second case was a 25 years old female. The tumor was situated in a nerve trunk of the thigh, and formed a multilobular bulbous swelling within the nerve. Microscopically, the tumor showed monomorphic spindle cells and revealed invasion of the epineurium and surrounding soft tissue. A brief review of the literature and a discussion on he histogenesis of the tumor were made.
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