Abstract

Xanthogranulomatous pyelonephritis is a rare variety of chronic pyelonephritis and characterized pathologically by extensive destruction of renal parenchyme with presence of granulomas, abscesses, myriads of lipid-laden macrophages(foam cells), plasma cells, and lymphocytes, and is involved virtually always unilateral kidney. It’s etiology and pathogenesis are unclear but four possible factors are suggested: 1. an abnormality in lipid metabolism. 2. previous in effective antibiotic therapy for a relatively benign urinary tract infection. 3. a specific offending infectious agent. 4. obstruction of the urinary tract at some level. We have recently experienced one case of Xanthogranulomatous pyelonephritis in 23 year old korean female.