Abstract

The authors isolated 27 organisms (11 species) from the patients, observed the effective-ness of antibiophagine to the organisms in vitro, and compared the results with the sensitivities to various antibiotics. The results were summarized as follows: 1. In vitro antibiophagine inhibited to a remarkable extent the growth of Salmonella group D, E. coli, Shigella, Proteus and Enterobacter and inhibited moderately the growth of Staphy-lococci and Salmonella group A. 2. When grossly negative growth on 24-hour culture subcultured, some strains of Salmonella group D, E. coli, Shigella, Klebsiella and Proteus were not cultivated. 3. Some of Staphylococcus albus, Salmonella group A and Enterococcus which proved resistant to the action of various antibiotics were sensitive to antibiophangine. A strain of Staphylococcus aureus, not effective to antibiophagine, was sensitive to some antibiotics. 4. Antibiophagine inhibited the growth of Pneumococcus and Enterobacter of which bacteriophage are not contained in it.