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The Korean Journal of Pathology 1996;30(3): 266-268.
Sertoli-Leydig Cell Tumor with a Coexisting Brenner Tumor of the Ovary.
Ji Youn Bae, Sang Pyo Kim, Kwan Kyu Park, Soon Do Cha
1Department of Pathology, Keimyung University School of Medicine, 700-310 Taegu, Korea.
2Department of Obsterics & Gynecology, Keimyung University School of Medicine, 700-310 Taegu, Korea.
Sertoli-Leydig cell tumor or Brenner tumor is a relatively rare ovarian tumor. Other associated elements in the form of epithelial, mesenchymal, and tumor components of each tumor have been reported. The Sertoli-Leydig cell tumor with a Brenner tumor element has not been documented in the literature, so we are reporting on a case of Sertoli-Leydig cell tumor coexisting with a Brenner tumor. This 62-year-old woman presented with a 4 year history of lower abdominal mass and vaginal bleeding. Exploratory laparotomy was done. The left ovary showed a multiseptated, cystic, yellow-white solid mass, measuring 17.0x13.0x5.0 cm and weighing 985.0 gm. Microscopic examination revealed a tubular or trabecular arrangement of the Sertoli cells and variable numbers of Leydig cells. There were several tumor nests with cystic spaces composed of ovoid cells showing longitudinal nuclear grooving. Sarcomatoid or heterologous elements were not found.
Key Words: Sertoli-Leydig cell tumor; Brenner tumor; Ovary