Warning: mkdir(): Permission denied in /home/virtual/lib/view_data.php on line 81

Warning: fopen(upload/ip_log/ip_log_2024-03.txt): failed to open stream: No such file or directory in /home/virtual/lib/view_data.php on line 83

Warning: fwrite() expects parameter 1 to be resource, boolean given in /home/virtual/lib/view_data.php on line 84
DNA Ploidy in Anaplastic Carcinoma of the Thyroid Gland by Image Analysis.
Skip Navigation
Skip to contents

J Pathol Transl Med : Journal of Pathology and Translational Medicine

OPEN ACCESS
SEARCH
Search

Articles

Page Path
HOME > J Pathol Transl Med > Volume 6(1); 1995 > Article
Original Article DNA Ploidy in Anaplastic Carcinoma of the Thyroid Gland by Image Analysis.
Ji Shin Lee, Min Cheol Lee, Chang Soo Park, Sang Woo Juhng
Journal of Pathology and Translational Medicine 1995;6(1):10-17
DOI: https://doi.org/
Department of Pathology, Chonnam University Medical School, Korea.
  • 1,467 Views
  • 11 Download
  • 0 Crossref
  • 0 Scopus

Anaplastic carcinoma of the thyroid gland is one of the most malignant tumors. Recently, DNA ploidy measured by flow cytometry and image analysis has been suggested as an additional useful indicator of tumor behavior. Studies on the occurrence and clinical significance of DNA aneuploidy in anaplastic carcinoma of the thyroid are rare. In this study, the pattern of DNA ploidy was measured by image analysis on Papanicolaou stained slides in four cases of anaplastic carcinoma and also measured by flow cytometry using paraffin blocks in two cases. In all cases of anaplastic carcinoma. DNA aneuploidy was found by image analaysis. By flow cytometry, one case had a diploid peak and the other case had an arieuploid peak. According to the above results, we conclude that anaplastic carcinoma of the thyroid glands have a high incidence of DNA aneuploidy and image analysis using Papanicolaou stained slides is a useful method in detecting DNA aneuploidy.

Related articles

J Pathol Transl Med : Journal of Pathology and Translational Medicine