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The Korean Journal of Pathology 1993;27(1): 78-80.
Primary Transitional Cell Carcinoma of the Ovary: A case report.
Eun Kyung Kim, Sung Ran Hong, Jae Uk Shim, Hy Sook Kim
1Department of Pathology, Cheil General Hospital, Seoul, Korea.
2Department of Obstetrics & Gynecology, Cheil General Hospital, Seoul, Korea.
Primary ovarian transitional cell carcinoma(TCC) is a recently described, distinct subtype of ovarian carcinoma resembling TCC of the urinary bladder. TCC differs from malignant Brenner tumor(MBT) by absence of benign or proliferative Brenner component and prominent stromal calcification. TCC also represents a high-stage tumor with more aggressive biologic behavior than MBT, but it has a relatively favorable response to chemotherapy. TCC may arise from the pluripotential surface epithelium of the ovary or from the cells with urothelial differentiation, rather than from a benign or proliferative Brenner tumor precursors. We report a case of pure form of primary TCC presenting as a left ovarian mass in 45-year-old woman.
Key Words: Transitional cell carcinoma; Malignant Brenner tumor; Ovary