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What's new in molecular genetic pathology 2026: emerging biomarkers for personalized cancer therapies
Umberto Maccio
Received November 24, 2025  Accepted January 3, 2026  Published online January 3, 2026  
DOI: https://doi.org/10.4132/jptm.2026.01.03    [Epub ahead of print]
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New and emerging biomarkers and current molecular assays for the most prevalent and lethal cancers worldwide—breast, lung, prostate, and colorectal cancer—are described. Notably, HER2-low breast cancer and HER2-mutated non-small cell lung cancer have recently been recognized as targetable entities. In addition, various tissue-based analyses are now available to assess prognosis and the risk of relapse in prostate cancer.

J Pathol Transl Med : Journal of Pathology and Translational Medicine
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