Journal of Pathology and Translational Medicine

Original Article

Epidermolysis Bullosa Simplex Generalisata.: Kye Yong Song, Joong Seok Seo, Sung Hye Park, Je G Chi, Kwang Hyun Cho; Korean J Pathol. 1992;26(1):62-65.

Abstract PDF: We report a case of epidermolysis bullosa simplex occurred in a 12-year-old girl, who presented with intractable bullous lesions of the hands and feet after minor traumas ever since her early neonatal period. The bullous lesions were noted on the 2nd and 4th webs of the fingers and dorsum of the hands as well as on the skin of the ankle. The lesions were healed without scar formation. Family history was not contributary and seasonal pattern was not noted. Histologic sections revealed intraepidermal bullae just above the well preserved basement membrane. Electron microscopic findings revealed cytolysis of basal cells with preservation of the basement membrane, indicating the epidermal type of epidermolysis bullosa simplex.

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