Journal of Pathology and Translational Medicine

Yong Soo Choi

3 Articles

Size of Non-lepidic Invasive Pattern Predicts Recurrence in Pulmonary Mucinous Adenocarcinoma: Morphologic Analysis of 188 Resected Cases with Reappraisal of Invasion Criteria: Soohyun Hwang, Joungho Han, Misun Choi, Myung-Ju Ahn, Yong Soo Choi; J Pathol Transl Med. 2017;51(1):56-68. Published online October 16, 2016; DOI: https://doi.org/10.4132/jptm.2016.09.17

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Background
We reviewed a series of 188 resected pulmonary mucinous adenocarcinomas (MAs) to clarify the prognostic significance of lepidic and non-lepidic patterns.
Methods
Non-lepidic patterns were divided into bland, non-distorted acini with uncertain invasiveness (pattern 1), unequivocal invasion into stroma (pattern 2), or invasion into alveolar spaces (pattern 3).
Results
The mean proportion of invasive patterns (patterns 2 and 3) was lowest in small (≤ 3 cm) tumors, and gradually increased in intermediate (> 3 cm and ≤ 7 cm) and large (> 7 cm) tumors (8.4%, 34.3%, and 50.1%, respectively). Adjusted T (aT) stage, as determined by the size of invasive patterns, was positively correlated with adverse histologic and clinical features including older age, male sex, and ever smokers. aTis tumors, which were exclusively composed of lepidic pattern (n = 9), or a mixture of lepidic and pattern 1 (n = 40) without any invasive patterns, showed 100% disease- free survival (DFS). The aT1mi tumors, with minimal (≤ 5 mm) invasive patterns (n = 63), showed a 95.2% 5-year DFS, with recurrences (n = 2) limited to tumors greater than 3 cm in total size (n = 23). Both T and aT stage were significantly associated with DFS; however, survival within the separate T-stage subgroups was stratified according to the aT stage, most notably in the intermediatestage subgroups. In multivariate analysis, the size of invasive patterns (p = .020), pleural invasion (p < .001), and vascular invasion (p = .048) were independent predictors of recurrence, whereas total size failed to achieve statistical significance (p = .121).
Conclusions
This study provides a rationale for histologic risk stratification in pulmonary MA based on the extent of invasive growth patterns with refined criteria for invasion.

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Distinct Recurrence Pattern and Survival Outcomes of Invasive Mucinous Adenocarcinoma of the Lung: The Potential Role of Local Therapy in Intrapulmonary Spread
Dong Woog Yoon, Soohyun Hwang, Tae Hee Hong, Yoon-La Choi, Hong Kwan Kim, Yong Soo Choi, Jhingook Kim, Young Mog Shim, Jong Ho Cho
Annals of Surgical Oncology.2024; 31(1): 201. CrossRef
Pulmonary invasive mucinous adenocarcinoma
Wei‐Chin Chang, Yu Zhi Zhang, Andrew G Nicholson
Histopathology.2024; 84(1): 18. CrossRef
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International Journal of Surgical Pathology.2024; 32(5): 926. CrossRef
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Journal of Cancer Research and Clinical Oncology.2020; 146(5): 1291. CrossRef
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Wei-Chin Chang, Yu Zhi Zhang, Eric Lim, Andrew G Nicholson
American Journal of Clinical Pathology.2020; 154(1): 88. CrossRef

A Rare Case of Pulmonary Papillary Adenoma in Old Aged Woman: A Brief Case Report: In Ho Choi, Joungho Han, Jung Won Moon, Yong Soo Choi, Kyung-Jong Lee; Korean J Pathol. 2014;48(1):66-68. Published online February 25, 2014; DOI: https://doi.org/10.4132/KoreanJPathol.2014.48.1.66

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Papillary adenoma of the lung: A case report and literature review
Li-Qian Chen, Mai-Qing Yang, Su-Mei Gao, Zheng-Jiang Wang, Hong-Tao Xu
Experimental and Therapeutic Medicine.2024;[Epub] CrossRef
Pulmonary papillary adenoma with malignant potential: a case report and literature review
Ping Liu, Junjian Feng, Min Yang, Jingqiu Chen, Luyao Fu, Junxu Lu
Diagnostic Pathology.2022;[Epub] CrossRef
Central papillary adenoma of the lung diagnosed in a bronchoscopy-guided FNA: Cytological and histological characterization of this rare entity
Iñigo Gorostiaga, Adriano Martinez-Aracil, Blanca Catón, Alvaro Perez-Rodriguez
Revista Española de Patología.2021; 54(3): 206. CrossRef
Retrospective study of clinical and pathologic features of pulmonary papillary adenoma
Pengcheng Zhou, Wei Yu, Li Wang, Qianming Xia, Keling Chen
Medicine.2020; 99(44): e23066. CrossRef
Pulmonary papillary adenoma presenting in central portion: a case report
Xu-Yong Lin, Qiang Han, En-Hua Wang, Yong Zhang
Diagnostic Pathology.2015;[Epub] CrossRef

Micropapillary Mucinous Adenocarcinoma of the Lung: A Brief Case Report: In Ho Choi, Boin Lee, Joungho Han, Chin A Yi, Yong Soo Choi, Jin Seok Ahn; Korean J Pathol. 2013;47(6):603-605. Published online December 24, 2013; DOI: https://doi.org/10.4132/KoreanJPathol.2013.47.6.603

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James J. Saller, Theresa A. Boyle
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Yang Qu, Nanying Che, Dan Zhao, Chen Zhang, Dan Su, Lijuan Zhou, Lili Zhang, Chongli Wang, Haiqing Zhang, Lixin Wei
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Cytomorphological identification of advanced pulmonary adenocarcinoma harboring KRAS mutation in lymph node fine‐needle aspiration specimens: Comparative investigation of adenocarcinoma with KRAS and EGFR mutations
Dae Hyun Song, Boram Lee, Yooju Shin, In Ho Choi, Sang Yun Ha, Jae Jun Lee, Min Eui Hong, Yoon‐La Choi, Joungho Han, Sang‐Won Um
Diagnostic Cytopathology.2015; 43(7): 539. CrossRef

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