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The Korean Journal of Pathology 1992;26(2): 164-170.
Mullerian Adenosarcoma of the Ovary with Sex Cord-Stromal Differentiation: A case report.
Sun Hee Sung, Soon Won Hong, Kyu Rae Kim, Woo Ick Yang
1Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
2Cha Women's Hospital.
Mullerian adenosarcoma is a tumor composed of a mixture of glandular and stromal elements in which the glandular component appear to be neoplastic but, histologically, benign with the stromal component showing varying degrees of malingancy. We report a case of ovarian m llerian adenosarcoma with sex cord stroma differentiation in the stromal components. A 57 year-old female who presented with palpable mass in the right lower abdomen had undergone through salingo-oophorectomy. Grossly, the ovary was multicystic, and partly showed a solid appearance with multiple polypoid projections into the dilated cystic spaces. On microscopic examination, the tumor consisted of benign to borderline epithelial glands that were lined by variety of mullerian epithelia and sarcomatous component with sex cord-stromal elements, which include sertoliform tubules, Leydig cell like clusters, and granulosa cells.
Key Words: Ovary; Mullerian adenosarcoma; Sex cord stromal differentiation