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The Korean Journal of Pathology 1990;24(4): 489-496.
Clear Cell Adenocarcinoma of the Urinary Bladder Accompanied by Vesical Endometriosis.
Eun Kyung Han, So Yeon Park, Nam Hoon Cho, Woo Ik Yang, Chanil Park
Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
ABSTRACT
A case of clear cell adenocarcinoma arising in the female urinary bladder, which is accompanied by endometriosis of the urinary bladder and the uterus, is reported. The carcinoma protruded into the vesical lumen as a fungating mass, and had a tubulocyotic pattern. The tumor cell had intracytoplasmic glycogen and electron microscopically short microvilli on their surface, resembling clear cell acenocarcinoma of the female genital tract including ovary. This is the fourth case report of clear cell adenocarcinoma complicating vesical endometriosis, and may support the view that clear cell carcinome arises from endometriosis which, in turn, from the Mullerian remnant.
Key Words: Clear cell adenocarcinoma; Mesornephric carcinoma; Endometriosis; Mullerian duct; Wolffian duct