| Home | E-Submission | Sitemap | Contact Us |  
The Korean Journal of Pathology 1990;24(2): 166-170.
Rhinoscleroma: A case report.
Joung Ho Han, Joon Mee Kim, In Sun Kim, Seung Young Paik
Department of Pathology, Korea University Hospital, Seoul, Korea.
ABSTRACT
Rhinoscleroma, or scleroma, is a chronic, slowly progressing granulomatous disease involving the upper respiratory tract, especially the nasal vestibules, choanae, pharynx, and larynx. Almost certainly the causative agent is Klebsiella rhinoscleromatis. The disease occurs frequently in Eastern Europe, the Middle East, and parts of Latin America, but it is hard to find such case in Korea. We prisent a case of rhinoscleroma involving the nasal vestibule in a 18-year-old male who was admitted due to nasal obstruction for 5 years and epistaxis for 2 months. The resected specimen was an irregular polypoid mass with relatively firm consistency and measured 3 cm in the largest diameter. Microscopically, the lesion was characterized by extensive fibrosis and inflammatory cell infiltration. The infiltrates consisted of predominantly lumphocytes, plasma cells, foamy or granular histiocytes which were singly scattered or grouped in clusters. In the cytoplasm of the histiocytes, round slightly basophilic bodies were noted. Warthin-Starry satin showed short positive rods within the cytoplasm of the cell (Mikulicz cell). Electron microscopically, the cytoplasm of Mikulicz cells contained large, round or irregular shaped clear vacuoles in which numerous Klebsiella bacilli attached to the boundaries of the vaculoes were noted. With higher magnifications, the bacilli were seen as roung or rod-shaped organisms.
Key Words: Rhinoscleroma; Klebsiella rhinoscleromatis; Mikulicz cell
TOOLS
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
CrossRef TDM  CrossRef TDM
  E-Mail
Share:      
METRICS
733
View
0
Download
Related articles
Kaposi's Sarcoma -A case report-  1984 December;18(4)
Mucopolysaccharidosis -A case report-  1984 December;18(4)
Anisakiasis in Terminal Ileum -A case report-  1984 December;18(4)
Acardius Acephalus -A case report-  1984 January;18(2)
Adrenal Cortical Carcinoma -A case report-  1983 January;17(4)