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The Korean Journal of Pathology 1989;23(4): 476-481.
Hurthle Cell Tumor of the Thyroid Gland in an Infant: A case report.
Kyoung Ho Kim, Mi Kyung Lee, Dong Hwan Shin, Tae Seung Kim, Eui Ho Hwang
1Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
2Department of General Surgery, Yonsei University College of Medicine, Seoul, Korea.
Hurthle cell tumors are an infrequent neoplasm of the thyroid gland in adults. Hurthle cell tumors represent 4. 5% to 10% of all primary thyroid epithelial neoplasms in the foreign literature. It has been known as Hurthle cell tumor since Ewing was the first to use this term in 1928. Tumor occurring in an infant was described by Symmers(1941) and Morrow(1945). The authors experienced a case of congenital Hurthle cell tumor of the thyroid gland in a 2 months old boy. He was admitted to the pediatric surgical department because of a growing mass in the neck since birth. Ultrasonogram showed a huge lobulated homogenous solid mass with medium level echogenicity in the region of the thyroid gland. Subtotal thyroidectomy of right lobe and total thyroidectomy of left lobe were done. The specimen measures 2x3x1.5 cm and 7x3x3 cm, respectively. It was an encapsulated, yellow gray firm and solid mass. The cut surface was smooth, glistening and homogenous. Microscopicully, the tumor was composed of tightly packed regular follicles lined by polyhedral, cuboidal, large cells with a granular acidophilic cytoplasms. The nuclei are vesicular, usually only a little bit larger than those of normal thyroid cells.
Key Words: Hurthle cell tumor; Thyroid gland; Infant