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The Korean Journal of Pathology 1987;21(4): 308-316.
Congenital Melanocytic Schwannoma in Ankle Joint Potentially Malignant: A case report.
Jong Tae Park, Chang Soo Park, Sang Woo Juhng, Kyu Hyuk Cho
Department of Pathology, Chonnam National University Medical School, Kwangju, Korea.
Congenital malignant melanocytic schwannoma in ankle joint was not reported on literature and it was a very interesting case. Light microscopically, melaninladen cells were mixed in abundant wavy spindle cells, some mitotic cells were also observed. Ultrastructurally, melanosomes in variable stages of development were scattered in the cytoplasm which had basal lamina. Collagen bundles were abundant in the intercellular connective tissue. It was histologically malignant tumor and clinically recurred. But in non-congenital potentially malignant melanocytic schwannoma which had been reported, reccurrence or distant metastasis were not noted. So, further clinical survey may be necessary for evaluation of the malignant behavior of this neoplasm.
Key Words: Schwannoma; Congenital; Melanocytic; Ankle