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The Korean Journal of Pathology 1987;21(1): 26-33.
Pseudosarcoma of the Esophagus: A case report with mapping, immunohistochemical and ultrastructural studies.
Soon Hee Jung, Young Bae Kim, Tai Seung Kim, Sang Ok Kwon, Soo Yong Kim
1Department of Pathology, Wonju College of Medicine, Yonsei University, Wonju, Korea.
2Department of Internal Medicine, Wonju College of Medicine, Yonsei University, Wonju, Korea.
3Department of General Surgery, Wonju College of Medicine, Yonsei University, Wonju, Korea.
ABSTRACT
So called pseudosarcoma of the esophagus is an extremely rare polypoid malignant tumor and a number of cases, totaling 19 cases have been reported in world literatures until 1985. The presenting case is an unique one of pseudosarcoma of the esophagus and we illustrated all microscopic features with mapping, immunoperoxidase stain for cytokeratin and electron microscopic findings to clarify the histogenesis of spindle cells. It is postulated that the spindle cells of pseudosarcoma are transformed from squamous carcinoma cells based on (1) morphological similarity between squamous epithelial cells and spindle cells, (2) positive reaction of immunoperoxidase staining for cytokeratin in the adjacent normal esophageal mucosa, squamous cell carcinoma, spindle cells and giant cells and (3) presence of transformation zone.
Key Words: Pseudosarcoma; Esophagus