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The Korean Journal of Pathology 1986;20(1): 112-115.
Exceptionally Good Lymphocytic Infiltration with Histiocytes and Multinucleated Giant Cells of Stomach Cancer: A case report.
Dongsoo Suk, Sook Hee Hong, Hye Kyung Yoon, Hyung Gin Kang
1Department of Pathology, Inje Medical College and Pusan Paik Hospital, Pusan, Korea.
2Department of Surgical, Pusan Blue Cross Hospital, Pusan, Korea.
Stomach of 34 year old man showed an early stage of the cancer with slight involvement of the superficial part of the inner muscle layer and accompanied with one metastatic lymph node. The cancer is that of medium differentiated adenocarcinoma. There is an heavy infiltration of lymphocytes mixed with histiocytic mononuclear cells and multinucleated giant cells. Some giant cells appear as Langhans' type suggesting phagocytic cells of their origin containing PAS positive materials in the cytoplasma. In other places, they appear as atrophic cancer nests suggesting that these tumor nests were arrested and undergone to regressive cellular process because of the over-whelming immunological pressure by the host.
Key Words: Stomach Cancer; Stromal Reaction; Granuloma of Stomach