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The Korean Journal of Cytopathology 2008;19(2): 178-182.
doi: https://doi.org/10.3338/kjc.2008.19.2.178
Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytology in the Diagnosis of a Gastrointestinal Stromal Tumor of the Stomach: A Case Report.
Lucia Kim, Hyung Gil Kim, Young Chae Chu, In Suh Park, Suk Jin Choi, Jee Young Han, Sun Hee Kim, Don Haeng Lee, Joon Mee Kim
1Department of Pathology, College of Medicine, Inha University, Incheon, Korea. jmkpath@inha.ac.kr
2Department of Gastroenterology, College of Medicine, Inha University, Incheon, Korea.
We report here a case of a gastrointestinal stromal tumor (GIST) in the stomach that was diagnosed by endoscopic ultrasound-guided fine needle aspiration cytology (EUS-FNA). A 67 year old male patient underwent regular check-ups for five years due to the presence of a submucosal tumor that was found in the fundus of the stomach incidentally. EUS-FNA was performed to evaluate the tumor, which had increased in size from 1cm to 2.8cm. A cytologic smear revealed cohesive sheets or clusters of spindle cells with elongated nuclei. Immunohistochemical staining revealed a strong positive reaction for c-kit and CD34, without any reaction for smooth muscle actin and Ki-67. Therefore, a diagnosis of GIST was made.
Key Words: Gastrointestinal stromal tumor; Endoscopy; Ultrasound-guided fine needle aspiration cytology; Immunohistochemistry