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The Korean Journal of Cytopathology 2003;14(1): 22-26.
Fine Needle Aspiration Cytology of Cystic Hypersecretory Intraductal Carcinoma of the Breast: Report of Two Cases.
Hee Jeong Cha, Dae Woon Eom, Jae Hee Suh
Department of Pathology School of Medicine, Ulsan University, Ulsan, Korea. heej0124@medimail.co.kr
ABSTRACT
Cystic hypersecretory carcinoma of the breast is a rare variant of ductal carcinoma of breast, first described in 1984 by Rosen and Scott. Histologically, it is characterized by the formation of dilated ducts and cysts containing an eosinophilic secretory product resembling thyroid colloid. Cytologic findings show a few clusters of atypical ductal epithelial cells in amorphous proteinaceous material with cracking artifact. Differential diagnosis include mucinous carcinoma and benign mucocele-like tumor. We present two cases of fine needle aspiration cytology of cystic hypersecretory intraductal carcinoma of the breast with a review of the literature.
Key Words: Breast; Neoplasm; Cystic hypersecretory carcinoma; Fine needle aspiration cytology