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The Korean Journal of Cytopathology 2001;12(1): 45-48.
Fine Needle Aspiration Cytology of Papillary-Cystic Variant of Acinic Cell Carcinoma of Salivary Gland: A Case Report .
Ah Won Lee, Jin Young Yoo, Seok Jin Kang, Byung Kee Kim
Department of Clinical Pathology, College of Medicine, The Catholic University, Seoul, Korea.
Acinic cell carcinoma(ACC) is the third common malignancy in major salivary gland. Fine needle aspiration cytology is a useful tool for the diagnosis of salivary gland lesions. However, some low grade malignancies, such as ACC and mucoepidermoid carcinoma show relatively high false negative rate, mainly due to deceptively benign cytomorphologic appearance. We experienced a papillary-cystic variant of ACC, having different cytopathologic features compared with those of classic ACC. Our case showed monolayered sheets and papillary clusters without any acinic structures or naked nuclei of the tumor cells. Foamy proteinaceous material was seen in the background. The tumor cells had a large amount of granular cytoplasm and eccentric nuclei. Many vacuolated or clear cells were also noted.
Key Words: Acinic cell carcinoma; Fine needle aspiration cytology; Salivary gland