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The Korean Journal of Cytopathology 1991;2(1): 43-50.
복강에 발생한 악성 상피성 중피종의 세침흡인생검
연세대학교 의과대학 병리학교실
Fine needle aspiration cytology of malignant epithelial mesothelioma of the peritoneum.
Sun Hee Sung, Kwang Gil Lee
Department of Pathology, Yonsei University, College of Medicine, Seoul, Korea
A case of malignant epithelial mesothelioma of the peritoneum diagnosed by fine needle aspiration cytology is described. The smear showed many individually scattered or clustered large round malignant epithelial cells intermingled with relatively small nonneoplastic mesothelial and mesenchymal cells. Papillary configurations with thick fibrous core were also seen. The malignant cells were virtually reminiscent of reactive mesothelial cells but they were larger in size and had more prominent nucleoli and more frequent binucleated or multinucleated cell formations than reactive mesothelial cells. The characteristic features of malignant cell of mesothelioma compared with the metastatic adenocarcinoma were relatively uniform cellular size, prominent round nucleoli, large round vesicular nuclei with finely granular chromatin pattern, smooth nuclear membrane, abundant glassy cytoplasm rather than bubbly mucin-containing cytoplasm and fuzzy cell border.
Key Words: Mesothelioma; Peritoneum; Aspiration cytology