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JPTM > Volume 45(4); 2011 > Article
The Korean Journal of Pathology 2011;45(4): 412-416.
doi: https://doi.org/10.4132/KoreanJPathol.2011.45.4.412
Parotid Gland Carcinosarcoma with Osteosarcoma as a Sarcomatous Component: A Case Report with Fine Needle Aspiration Cytologic Findings.
Se Min Jang, Young Jin Jun, Hulin Han, Ki Seok Jang, Seung Sam Paik
Department of Pathology, Hanyang University College of Medicine, Seoul, Korea. sspaik@hanyang.ac.kr
Carcinosarcoma of the salivary glands is a rare malignant tumor showing both malignant epithelial and mesenchymal components. Herein, we present a carcinosarcoma of the parotid gland in a 67-year-old man consisting of osteosarcoma and adenocarcinoma components with fine needle aspiration cytological findings. The tumor was composed predominantly of osteosarcoma and small areas of adenocarcinomatous components and a hyalinized nodule reminiscent of pleomorphic adenoma. The tumor showed infiltrative growth features with perineural, lymphatic, and vascular invasion. Despite postoperative adjuvant radiation therapy, multiple metastatic lesions occurred in the both lungs 5 months after surgery. As salivary gland carcinosarcoma has been known to demonstrate highly aggressive behavior, an accurate pathological diagnosis is prerequisite for appropriate treatment.
Key Words: Carcinosarcoma; Osteosarcoma; Adenocarcinoma; Fine-needle aspiration cytology; Parotid gland