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JPTM > Volume 45(2); 2011 > Article
The Korean Journal of Pathology 2011;45(2): 217-222.
doi: https://doi.org/10.4132/KoreanJPathol.2011.45.2.217
Fine Needle Aspiration Cytologic Findings of Angiosarcoma: Report of Two Cases.
Jin Xian Ji, Young Chae Chu, Lucia Kim, Suk Jin Choi, In Suh Park, Jee Young Han, Joon Mee Kim, Kyu Ho Kim, Ju Young Song
Department of Pathology, Inha University Hospital, Inha University School of Medicine, Incheon, Korea. ycchu@inha.ac.kr
ABSTRACT
Angiosarcoma is a rare malignant vascular neoplasm which can arise in any part of the body. Specific recognition of this neoplasm in cytological specimens is difficult in the absence of an ancillary method. Herein, we present the cytologic findings of two cases of angiosarcomas diagnosed on fine needle aspiration cytology. One case is a recurred angiosarcoma in the left chest wall and the other case is a lymphedema-associated angiosarcoma in the left lower leg. The cytologic findings of both cases are similar. Cytologic features that identified this neoplasm as an angiosarcoma included arborizing microtissue fragments, irregular anastomosing vascular spaces lined by atypical cells, microacini, intracytoplasmic lumen, and intracellular red blood cells, marked cell discohesiveness, spindle to ovoid, irregular, hyperchromatic nuclei, and elongated cytoplasmic processes with indistinct borders. This report emphasizes that when aspiration smears show vasoformative features in a bloody background, angiosarcoma should be included in the differential diagnosis.
Key Words: Angiosarcoma; Fine needle aspiration cytology