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The Korean Journal of Pathology 2010;44(6): 670-674.
doi: https://doi.org/10.4132/KoreanJPathol.2010.44.6.670
Spindle Cell Epithelioma, a So-called Benign Mixed Tumor of the Vagina: A Case Report.
Mee Hye Oh, Eun Ah Jung, Ji Hye Lee, Hyun Deuk Cho, Seung Ha Yang, Jeong Ja Kwak
1Department of Pathology, Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea. mhoh0212@hanmail.net
2Department of Pathology, Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.
We report a case of spindle cell epithelioma, a so-called benign mixed tumor of the vagina. The patient was a 35-year-old nulliparous woman who presented with a polypoid mass in the posterior wall of the lower vagina just above the hymenal ring. The tumor was relatively well-defined with an expansile margin and composed of stromal-type spindle cells with a myxoid stroma arranged in short fascicles and an irregular cord-like or reticular pattern. A few glandular structures lined by cuboidal cells with squamous metaplasia were also noted. Cellular atypia was not conspicuous and mitosis was not found. We examined this tumor immunohistochemically to identify the histogenesis. The coexpression of epithelial and mesenchymal markers in stromal-type spindle cells suggested a multipotential cell origin for this tumor. The patient has been well with no signs of recurrence during the 12 months after surgery.
Key Words: Epithelioma; Spindle cell; Mixed tumor; Vaginal neoplasms