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JPTM > Volume 44(6); 2010 > Article
The Korean Journal of Pathology 2010;44(6): 662-665.
doi: https://doi.org/10.4132/KoreanJPathol.2010.44.6.662
Primary Malignant Melanoma of the Male Urethra.
Seung Wook Lee, Eun Kyung Kim, Won Mi Lee, Jung Man Jo, Tag Keun Yoo, Jeong Yoon Kang
1Department of Urology, Eulji University School of Medicine, Seoul, Korea.
2Department of Pathology, Eulji University School of Medicine, Seoul, Korea. kek7402@eulji.ac.kr
ABSTRACT
Primary malignant melanoma occurring within the male urethra is very rare. Here we report a case of malignant melanoma of the urethra in a 74-year-old man. He presented with asymptomatic gross hematuria for 5 months. His glans penis and adjacent penile skin had become discolored black 10 years ago. Cystourethroscopy showed a smooth oval-shaped elevated mass in the fossa navicularis. There were no abnormal findings in the proximal urethra and urinary bladder. Computed tomography did not detect any inguinal lymph node enlargement or distant metastases. The patient underwent partial penectomy and ilioinguinal lymph node dissection. Grossly, the distal urethra revealed an ovoid pigmented nodule, that measured 1 x 0.5 cm. Microscopic findings showed a nodular malignant melanoma arising in the urethral mucosa with pagetoid spread to the epidermis of the glans penis. There were no recurrences over a period of 12 months after surgery without chemotherapy. This is the second case of a primary malignant melanoma of the male urethra in Korea.
Key Words: Urethra; Male; Melanoma