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The Korean Journal of Pathology 2010;44(1): 87-91.
doi: https://doi.org/10.4132/KoreanJPathol.2010.44.1.87
A Case of Gastric Carcinosarcoma with Neuroendocrine and Smooth Muscle Differentiation.
Se Min Jang, Si Hyong Jang, Kyueng Whan Min, Woong Na, Young Jin Jun, Seung Sam Paik
Department of Pathology, Hanyang University College of Medicine, Seoul, Korea. sspaik@hanyang.ac.kr
Carcinosarcoma of the stomach is a rarely occurring malignant biphasic tumor that consists of both carcinomatous and sarcomatous components simultaneously in a single tumor. The common carcinoma component is tubular or papillary adenocarcinoma and the mesenchymal sarcomatous components are variable and these include leiomyosarcoma, rhabdomyosarcoma, osteosarcoma and chondrosarcoma. However, neuroendocrine carcinomatous differentiation in the carcinomatous component is extremely rare. We present here a rare gastric carcinosarcoma that demonstrated neuroendocrine carcinomatous and leiomyosarcomatous differentiation in a 47-year-old man.
Key Words: Stomach; Carcinosarcoma; Neurosecretory systems; Leiomyosarcoma