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The Korean Journal of Pathology 2009;43(1): 88-91.
doi: https://doi.org/10.4132/KoreanJPathol.2009.43.1.88
Intraosseous Neurilemmoma of the Mandible: A Case Report.
Kyu Yun Jang, Woo Sung Moon, Ho Sung Park
Department of Pathology, Institute for Medical Science, Chonbuk National University Medical School, Jeonju, Korea. hspark@chonbuk.ac.kr
Neurilemmoma (Schwannoma) is a benign nerve sheath tumor that's composed entirely of well-differentiated Schwann cells. Intraosseous neurilemmomas are rare and they represent less than 1% of all benign primary bone tumors. We report here on an additional case of intraosseous neurilemmoma that was located in the mandible of a 77-year-old woman. CT revealed an expansile, well-defined lesion on the right side of the mandibular body with thinning of the cortex. The lesion was surgically removed and it was found to be a 2x1.7 cm-sized, bright yellowish, hard mass with hemorrhage and cyst formation. Histologically, the mass was a moderately cellular neoplasm and it showed distinct nuclear palisading, numerous Verocay bodies and tumor cells that were positively immunohistostained for S-100 protein. Two months after the operation, the patient has remained in a good condition with no signs or symptoms of tumor recurrence.
Key Words: Mandibular neoplasms; Neurilemmoma; Bone neoplasms