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The Korean Journal of Pathology 2008;42(6): 396-400.
Adenocarcinoma Arising in Type 1 Congenital Cystic Adenomatoid Malformation: A Case Report and Review of the Literature.
Jinyoung Yoo, Sun Mi Lee, Ji Han Jung, Myeong Im Ahn, Deog Gon Cho, Seok Jin Kang, Kyo Young Lee
1Department of Pathology, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Korea. sjkang@vincent.cuk.ac.kr
2Department of Diagnostic Radiology, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Korea.
3Department of Thoracic Surgery, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Korea.
ABSTRACT
Malignancies in congenital cystic adenomatoid malformations (CCAMs) of the lung are rare. We report a 41-year-old male patient with a pulmonary cystic lesion suspicious for CCAM, unrecognized until the patient was 40 years of age, and which subsequently became more consolidated during the interval between initial presentation and surgery. Microscopic examination of the resected specimen revealed features of type 1 CCAM with a mucinous adenocarcinoma, metastatic to the mediastinal lymph nodes. This case illustrates the importance of prompt surgical resection for all suspected CCAMs, especially those discovered in adulthood.
Key Words: Congenital cystic adenomatoid malformation; Adenocarcinoma