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The Korean Journal of Pathology 2008;42(5): 317-322.
Solitary Splenic Metastases from Uterine Cervical Cancer: Case Reports and Review of the Literature.
Jo Heon Kim, Yoo Duk Choi, Jae Hyuk Lee, Jong Hee Nam, Sang Woo Juhng, Yang Seok Koh, Chol Kyoon Cho, Chan Choi
1Department of Pathology, Chonnam National University Medical School, Gwangju, Korea. cchoi@chonnam.ac.kr
2Department of Surgery, Chonnam National University Medical School, Gwangju, Korea.
3Brain Korea 21 Project for Biomedical Human Resources Center at Chonnam National University, Gwangju, Korea.
ABSTRACT
Splenic metastasis from gynecologic tumors is extremely rare, especially in the absence of apparent disease at other sites. We report two patients that underwent splenectomy for a solitary splenic metastasis from uterine cervical carcinoma. In case 1, a 54-year-old woman with FIGO Stage IIb squamous cell carcinoma of the uterine cervix treated with radiotherapy and chemotherapy developed a solitary splenic metastasis 10 months after initial treatment. In case 2, a 46-year-old woman with FIGO Stage IIb adenocarcinoma of the uterine cervix treated with radiotherapy and chemotherapy was found to have a solitary splenic metastasis 11 months after treatment. Thus all abdominal organs including the spleen must be evaluated for metastases during follow-up of gynecologic tumors.
Key Words: Uterine cervix; Gynecologic tumors; Splenic metastasis