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The Korean Journal of Pathology 2008;42(3): 181-184.
Juxtacortical Glomus Tumor of the Tibia with an Uncertain Malignant Potential.
Dae Woon Eom, Gil Hyun Kang, Hee Jin Lee, Soo Jung Choi, Jae kwang Hwang
1Department of Pathology, University of Ulsan College of Medicine, Gangneung, Korea. edwjyh@gnah.co.kr
2Department of Radiology, University of Ulsan College of Medicine, Gangneung, Korea.
3Department of Orthopedic Surgery, University of Ulsan College of Medicine, Gangneung, Korea.
ABSTRACT
Glomus tumors are mesenchymal neoplasms that are composed of modified smooth muscle cells of the normal glomus body. Most glomus tumors are benign and they occur in the distal extremities, and particularly the subungual lesions that occur in the hand, the wrist and the foot. We report here on a case of a solid type glomus tumor that had an uncertain malignant potential with a juxtacortical location at the distal tibia, and there were no neoplastic erosion of the cortical surface and no periosteal reaction. The tumor cells showed mild nuclear atypia and moderate mitotic activity (3-5/10HPF). Prominent intranuclear cytoplasmic pseudoinclusions were also observed. This case is interesting due to the very unusual tumor location of the juxtacortical area of the long bone, the atypical histologic features and the unique cytological finding of cytoplasmic intranuclear inclusions throughout the tumor cells.
Key Words: Glomus tumor; Juxtacortical; Intranuclear inclusion; Tibia