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The Korean Journal of Cytopathology 1998;9(2): 233-233.
Fine Needle Aspiration Cytology of Clear Cell Sarcoma: A Case Report.
Sung Chul Lim, You Kyung Chung, Dong Chool Kim, Yoon Kyung Lee, Eun Taik Shin
Department of Pathology, College of Medicine, Chosun University.
Clear cell sarcoma(CCS) is an uncommon soft tissue sarcoma that occurs in tendons and aponeuroses, usually of the lower extremities and is believed to be of neural crest origin that have a capability to produce melanin. These tumors commonly metastasize and have a very poor prognosis. The fine needle aspiration cytologic finding of CCS is not well documented. We recently experienced a case of CCS. The patient was a 54-year-old male with painful swelling of the right inguinal area. Fine needle aspiration cytology revealed polygonal or fusiform tumor cells with clear or granular cytoplasm and vesicular nuclei containing one or two nucleoli. Im munohistochemical staining for S-100 protein and HMB-45 revealed strong positivity, and variable developing stages of premelanosomes were observed by electron microscopy in the excised specimen.
Key Words: Clear cell sarcoma; Fine needle aspiration cytology