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The Korean Journal of Cytopathology 1991;2(1): 1-7.
Hodgkin 병의 세포학적 검색
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한양대학교 의과대학 병리학교실
Cytologic findings of Hodgkin's disease with special emphasis on Reed-Sternberg cells and their variants.
Young Hyeh Ko, Chan Pil Park, Jung Dal Lee
Department of Pathology, School of Medicine, Hanyang University, Korea
Cytologic findings from five cases with variable types of Hodgkin' disease were reviewed with special emphasis on the Reed-Sternberg (R-S) cells and their variants. Typical R-S and Hodgkin's cells were mono- or binucleated, and nuclei had rounded smooth contour. Acidophilic prominent nucleoli with perinucleolar halo were conspicuous. In comparison to typical Reed-Sternberg cells, L & H (lymphocytic and histiocytic) cells in the lymphocyte predominant type tended to show pop-corn like irregular nuclear contour and to lack the prominent nucleoli. Lacunar cells in the nodular sclerosis type had multilobated nuclei with prominent acidophilic nucleoli. There was no prominent perinucleolar halo in L & H and lacunar cells. In conjuction with the number of Reed-Sternberg cells and back ground findings observed on the smears, the characteristic features of R-S cells and their variants allowed to make typing of Hodgkin's disease.
Key Words: Hodgkin's disease; Reed-Sternberg cells; Lymph node Aspiration cytology
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