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The Korean Journal of Pathology 2005;39(3): 197-199.
Aspergillous Hypophysitis: A Case Report.
Jeana Kim, Leeso Maeng, Je Hoon Lee, Kyoung Mee Kim, Anhi Lee, Chang Suk Kang
Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea. kkmkys@catholic.ac.kr
ABSTRACT
Aspergillous hypophysitis is an unusual cause of sella turcica enlargement, and this malady has a clinical presentation as a pituitary tumor, and especially as a pituitary adenoma. We report here on a case of aspergillous hypophysitis that developed in a 37-year-old healthy woman. She first experienced a blurred vision with amenorrhea and galactorrhea. Three months later, the CT scan revealed an intrasellar mass. The patient underwent a transsphenoidal exploration of the sella turcica for a presumed pituitary tumor. Histologically, the pituitary displayed necrotizing granuloma with the acutely branching fungal hyphae of Aspergillus.
Key Words: Aspergillosis; Pituitary gland
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