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The Korean Journal of Pathology 2005;39(1): 54-58.
Inflammatory Myofibroblastic Tumor of the Breast: A Case Report.
Myoung Ja Chung, So Yeong Oh, Kyu Yun Jang, Woo Sung Moon, Myoung Jae Kang, Dong Geun Lee
1Department of Pathology, Chonbuk National University Medical School, Jeonju, Korea. mjchung@chonbuk.ac.kr
2Research Institute of Clinical Medicine, Chonbuk National University Medical School, Jeonju, Korea.
3Namwon Medical Center, Namwon, Korea.
Inflammatory myofibroblastic tumor (IMT) is characterized by a clonal proliferation of myofibroblasic spindle cells, and this is accompanied by a lymphoplasmacytic infiltration. In the majority of cases, this disease has occurred in the lungs and only 9 cases of IMT in the breast have been previously reported. We report here on an IMT in a 25-year-old-female who presented with a palpable mass in the right breast. Histologically, it was characterized by plump spindle cells admixed with prominent inflammation, that was composed of lymphocytes and plasma cells. Immunohistochemically, the spindle cells were positive for vimentin and -smooth muscle actin.
Key Words: Inflammatory myofibroblastic tumor; Breast